Senior Investigator/Chief - Genome Integrity & Structural Biology Laboratory

Job Summary

The National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health (NIH), is recruiting for a Senior Investigator to serve as Chief of the Genome Integrity and Structural Biology Laboratory (GISBL) within the Division of Intramural Research. The NIEHS is located in Research Triangle Park (RTP), near to the University of North Carolina, North Carolina State University, North Carolina Central University and Duke University. 

The NIEHS is a premier research institute where intramural investigators study a wide range of important biologic questions related to effects of the environment on human health. GISBL is composed of seven independent research groups that study fundamental mechanisms of genetic stability and instability, including DNA replication and repair utilizing state-of-the-art structural biology techniques, genetics, biochemistry and cell biology to provide insights into biological processes that modulate the effects of environmental exposures on human health. The GISBL also contains four state-of-the-art core facilities that provide computational chemistry and molecular modeling, cryo-electron microscopy (cryoEM), NMR, and x-ray crystallography support to all of NIEHS and, in the case of cryoEM, for other NIH institutes.

Required Qualifications

The ideal candidate will be tenure-eligible based on an outstanding record of scholarly achievement, leadership capabilities, and broad interests in understanding biological processes involved in mutagenesis, genome stability, allergenicity, mitochondrial function, inflammation, and epigenetic regulation.  In addition to directing an independent research program, the Chief will be responsible for leading GISBL and providing vision and directions as research in genome integrity, structural biology and environmental health science continues to evolve. Principal investigators in the NIH intramural program engage directly in high risk/high reward research with postdoctoral fellows, students, and support staff, and collaborate with colleagues to solve important scientific problems. Applicants should have a Ph.D., M.D., or equivalent doctoral degree in a relevant field, and a demonstrated interest in investigating fundamental mechanisms of genetic stability and instability. 

Appointees may be a US citizen, Legal Permanent Resident or non-US citizen who are eligible for a valid work authorization.

This position is subject to a background investigation.

Benefits

The successful candidate for this position will be eligible for a tenured appointment, and will receive a salary commensurate with experience and accomplishments. The successful candidate will receive full Federal benefits, including leave, health and life insurance, retirement, and savings plan (401K equivalent). 

Equal Employment Opportunity

The NIH NIEHS encourages the application and nomination of qualified women, minorities, and individuals with disabilities. The United States Government does not discriminate in employment on the basis of race, color, religion, sex (including pregnancy and gender identity), national origin, political affiliation, sexual orientation, marital status, disability, genetic information, age, membership in an employee organization, retaliation, parental status, military service, or other non-merit factor. Equal Employment Opportunity (EEO) for federal employees & job applicants.

Standards of Conduct/Financial Disclosure

If selected, you will be required to complete a Confidential Financial Disclosure Report, OGE Form 450 to determine if a conflict or an appearance of a conflict exists between your financial interest and your prospective position with the agency.

Foreign Education

Applicants who have completed part or all of their education outside of the U.S. must have their foreign education evaluated by an accredited organization to ensure that the foreign education is equivalent to education received in accredited educational institutions in the United States. We will only accept the completed foreign education evaluation. For more information on foreign education verification, visit the National Association of Credential Evaluation Services (NACES) website. Verification must be received prior to the effective date of the appointment. Learn more about Foreign Education.

Reasonable Accommodation

NIH provides reasonable accommodations to applicants with disabilities. If you require reasonable accommodation during any part of the application and hiring process, please notify us. The decision on granting reasonable accommodation will be made on a case-by-case basis