NCI is seeking an exceptional and visionary leader to serve as its Associate Director, Developmental Therapeutics Program (DTP), Division of Cancer Treatment and Diagnosis (DTCD). This position reports directly to the Deputy Director, DCTD. The DCTD takes prospective detection and treatment leads, facilitates their paths facilitates their paths to clinical application, and expedites the discovery, development and initial and subsequent large-scale testing of new agents, biomarkers, novel imaging technology, and other therapeutic interventions (radiation, surgery, immunotherapy) in patients. Within the DCTD, the DTP is responsible for the coordination of NCI’s national preclinical treatment development program. DTP includes eleven branches responsible for managing large grant portfolios, as well as contract-driven therapeutics development and internal laboratories related to anti-cancer agent (small molecules, natural products, and biologics) discovery and development. Within the DCTD, DTP provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents including toxicology and pharmacology. This program manages a large grants portfolio, as well as contract-driven therapeutics development and internal laboratories related to drug discovery and development. For more information on DTP, go to https://dtp.cancer.gov/
The Associate Director is responsible for providing senior program and policy leadership in a widely diverse and highly complex scientific arena that encompasses: biopharmaceutical production under Good Manufacturing Practices (GMP); research and repositories of patient-derived models (PDMs), animal and human tumor cell lines, chemical agents, biologicals, and natural products; and grants management of multi-disciplinary technical specificities related to small synthetic compounds, natural products, biologics (cytokines, antibodies, oncolytic viruses and vectors), immune modulators and cell-based immunotherapy agents. The Associate Director coordinates major translational research initiatives aimed at bringing cutting edge research discoveries for the laboratory to patients. The work accomplished under the specific responsibilities within these cross-functional, multidisciplinary components of this position directly contribute to the establishment of industry guidelines, resources and essential collaborations.
Applicants must possess a doctoral level degree (e.g., Ph.D. or M.D.) in an academic field related to the health sciences or allied sciences appropriate to the work of the DTP. Must have extensive research experience in the field of cancer therapeutics and development, biologics, and scientific background supporting pre-clinical research focusing on discovery, development and evaluation of agents. The candidate must have an understanding of regulatory requirements and issues in the development of investigational agents and the ability to establish and maintain working relationships with physicians and scientists, the Food and Drug Administration, other Federal agencies, academic and research institutions, and the biotechnology and pharmaceutical industries. The Associate Director requires a scientist with experience and leadership skills in translation of cancer research through the interface to clinical development. Experience and knowledge of research programs related to the treatment of cancer are essential. The incumbent must have had extensive experience involving the development of investigational new anticancer agents. The candidate must have authored significant publications in the therapeutics field.
Salary is competitive and will be commensurate with the experience of the candidate not-to-exceed $248,000. A recruitment or relocation bonus may be available, and relocation expenses may be paid. A full package of federal Civil Service benefits is available, including: retirement, health and life insurance, long term care insurance, leave, and a Thrift Savings Plan (401K equivalent). The successful candidate may be subject to a background investigation and public financial disclosure requirements.
Equal Employment Opportunity
The United States Government does not discriminate in employment on the basis of race, color, religion, sex (including pregnancy and gender identity), national origin, political affiliation, sexual orientation, marital status, disability, genetic information, age, membership in an employee organization, retaliation, parental status, military service, or other non-merit factor. Equal Employment Opportunity (EEO) for federal employees & job applicants.
Standards of Conduct/Financial Disclosure
If selected, you will be required to complete a Confidential Financial Disclosure Report, OGE Form 450 to determine if a conflict or an appearance of a conflict exists between your financial interest and your prospective position with the agency.
This position has an education requirement. You are strongly encouraged to submit a copy of your transcripts (or a list of your courses including titles, credit hours completed and grades). Unofficial transcripts will be accepted in the application package. Official transcripts will be required from all selectees prior to receiving an official offer. Learn more about Foreign Education.
You can request a reasonable accommodation at any time during the application or hiring process or while on the job. Requests are considered on a case-by-case basis.