Job Summary
The NIHCC is a hospital solely dedicated to clinical research at the NIH campus in Bethesda, Maryland. The Clinical Center, known as Building 10, consists of the original part of the hospital, the Warren Grant Magnuson Clinical Center, and the newest addition, the Mark O. Hatfield Clinical Research Center. The two parts are connected to form one large building. The Clinical Center has been a leader in the “bench-to-bedside” concept. Its specialized hospital design places patient care units in close proximity to research laboratories. This model supports interaction and collaboration among investigators. Currently, there are about 1,600 clinical protocols in progress at the NIH Clinical Center. About half are studies of the natural history of disease, especially rare diseases, which often are not studied anywhere else. Most other studies are clinical trials, often the first tests of new drugs and therapies in people. The clinical trials at the NIHCC are predominantly Phase I and Phase II, often first-in-human to test safety and efficacy. 2023 over 6,000 new patients were treated at the NIHCC, over 3,000 inpatient admissions, and over 80,000 outpatient visits.
The National Institutes of Health (NIH) Clinical Center seeks a Senior Pharmacologist to work in the Clinical Pharmacology Laboratory.
The incumbent will perform a variety of duties, including:
- Acts as a pharmacogenetic expert and provides consultation, guidance, and assistance on commercial and investigational products and supportive care.
- Provide dosing modification recommendations to patients based on pharmacogenetic results.
- Conduct research in the field of pharmacogenetics to improve the safety and efficacy of therapeutics.
- Correlation of pharmacokinetic data with pharmacogenetic data for investigational products and FDA-approved medications.
- Serves as a drug information resource for researchers, clinicians, nurses, pharmacists, and other medical staff within the NIHCC.
- Serves on panels, task forces, working groups, and advisory committees as requested.
- Serves as a liaison to the clinical research teams.
- Develops and prepares materials for publication. Prepares and delivers scholarly papers and presentations to professional organizations and local, regional, and national meetings.
- Collaborates with researchers on clinical trials through writing or evaluating protocols, reviewing clinical trial concepts and protocols, serving as an Associate Investigator in clinical trials, and assisting with protocol coordination and implementation.
- Participates in outpatient clinic, inpatient rounds, clinic meetings, and tumor boards as applicable.
- Routinely teach pharmacogenetic/pharmacogenomics to the clinical fellows, other clinical trainees, and clinical staff within the ICs.
Eligibility
The selected individual must have a Doctor of Pharmacy (Pharm D.), with post-doctoral training, and based on publications, be considered an international leader in the field of pharmacogenetics.
Conditions of Employment
- Candidates must be US citizens.
- This position is subject to a background investigation.
Required Qualifications
To be eligible for this position, candidates must be a U.S. citizen, or U.S. National. Foreign nationals or legal permanent residents are not eligible for consideration. Candidates must indicate their U.S. citizenship status on their CV or within their email application submission.
In order to qualify for this position, candidates must possess either a doctoral-level degree in biomedicine or a biological related field, or a master's level or higher degree in:
- engineering
- bioinformatics
- or an emerging or related scientific field.
In addition, candidates must have at least one year of experience related to the position, including achievements in one or more of the following areas to demonstrate the individual has received recognition as an expert in the field:
- Has significant experience dealing with complex, precedent-setting evaluation, scientific policies or development issues (e.g., those associated with novel biomedical products, novel approaches to biomedical product manufacturing, or use of novel evaluation methods)
- Demonstrated cutting-edge expertise in a scientific or technical discipline critical to design, development, manufacturing, clinical performance assessment, or technical aspects of effective oversight of biomedical products
- Played a leadership role in planning and conducting public meetings to seek public input and communicate regulatory scientific policies
- Received invitations to speak at or chair major national or international meetings and symposia or
- Meets other criteria demonstrating sufficient rigor or accomplishment in a relevant or closely related activity or field that is necessary to the accomplishment of NIH's mission.
If you are a current Federal Title 5 employee, you must have one year of equivalent experience at the GS-14 level or above.
Benefits
A career with the U.S. Government provides employees with a comprehensive benefits package. As a federal employee, you and your family will have access to a range of benefits that are designed to make your federal career very rewarding. Learn more about federal benefits.
Equal Employment Opportunity
The United States Government does not discriminate in employment on the basis of race, color, religion, sex (including pregnancy and gender identity), national origin, political affiliation, sexual orientation, marital status, disability, genetic information, age, membership in an employee organization, retaliation, parental status, military service, or other non-merit factor. Equal Employment Opportunity (EEO) for federal employees & job applicants.
Standards of Conduct/Financial Disclosure
If selected, you will be required to complete a Confidential Financial Disclosure Report, OGE Form 450 to determine if a conflict or an appearance of a conflict exists between your financial interest and your prospective position with the agency.
Foreign Education
This position has an education requirement. You are strongly encouraged to submit a copy of your transcripts (or a list of your courses including titles, credit hours completed and grades). Unofficial transcripts will be accepted in the application package. Official transcripts will be required from all selectees prior to receiving an official offer. Learn more about Foreign Education.
Reasonable Accommodation
You can request a reasonable accommodation at any time during the application or hiring process or while on the job. Requests are considered on a case-by-case basis.